Discovery Square

World-leading medical practitioners, educators, researchers, and businesses connect at Discovery Square, just steps from Mayo Clinic.

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The Future of Your Business is Here

Discovery Square in Rochester, Minnesota is a 16 block sub-district built in collaboration with Mayo Clinic in a highly connected urban life science hub.

Accelerate Your Business


As a business operating in Discovery Square you will have meetings with Mayo Clinic Ventures staff for routine reviews of new Intellectual Property.

Thought Leaders

The collaboration can extend to opportunities for evaluation and co-development of new and existing technologies with input from distinguished clinicians and scientists.


Discovery Square businesses have a strategic workforce advantage. 
Mayo Clinic College of Medicine and Science offers the latest educational programs in biomedical research, medical and clinical education. World-class faculty also can tailor innovative training to meet your evolving staff needs.

Core Services

Core laboratory services available to Mayo Clinic researchers are also available to Discovery Square health care businesses.


Discovery Square is a unique entrepreneurial environment of businesses of all sizes. Vibrant, agile startups bring their unique energy to Discovery Square, while some of the largest and best-respected companies from around the world bring deep expertise to the community. All of this happens in an ecosystem designed to encourage and equip entrepreneurs.


Festivals, museums, dining, shopping and nightlife are all within walking distance of Discovery Square. Plus, nature’s beauty surrounds you with hiking and biking trails, trout streams and adventure throughout the region.


Brimming with life and activity, Discovery Square is nestled in the urban core of a city that consistently ranks among the Best Places to Live by Livability Magazine. A place where historic neighborhoods meet the social amenities of a vibrant downtown.

Featured Project

One Discovery Square

Signature spaces and ample amenities differentiate Discovery Square. Next to Mayo Clinic, this approximately 90,000 square-foot phase one building is designed with collaboration in mind to support the acceleration and translation of the most promising health-related therapies and technologies.

Anchored by Mayo Clinic programs in imaging, augmented human intelligence, regenerative medicine and advanced diagnostics.

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Our Collaborators

Our Team Is Here to Help

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    Chris Schad

    Director of Business Development – Discovery Square

    As your Discovery Square expert, Chris is able to answer any questions you have and walk you through the process of becoming Discovery Square’s newest tenant.